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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VAV2
All Species:
13.64
Human Site:
Y746
Identified Species:
37.5
UniProt:
P52735
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52735
NP_001127870.1
878
101289
Y746
S
L
L
E
L
V
E
Y
Y
Q
C
H
S
L
K
Chimpanzee
Pan troglodytes
XP_512321
790
91847
E659
I
S
I
K
Y
N
V
E
V
K
H
I
K
I
M
Rhesus Macaque
Macaca mulatta
XP_001099207
878
101303
Y746
S
L
L
E
L
V
E
Y
Y
Q
C
H
S
L
K
Dog
Lupus familis
XP_850040
876
100535
Y744
S
L
L
E
L
V
E
Y
Y
Q
C
H
S
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q60992
868
99897
Y736
S
L
L
E
L
V
E
Y
Y
Q
C
H
S
L
K
Rat
Rattus norvegicus
P54100
843
97935
N710
F
A
I
S
I
K
Y
N
V
E
V
K
H
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505586
846
97900
V714
S
I
K
F
N
D
E
V
K
H
I
K
V
V
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NHV9
793
91337
A662
T
A
H
E
T
M
Y
A
L
S
L
K
T
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q45FX5
1007
113536
N860
F
L
V
R
Y
S
K
N
R
K
Q
T
A
I
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.2
99.6
90.2
N.A.
94.7
51.3
N.A.
83.7
N.A.
N.A.
N.A.
N.A.
29.6
N.A.
25.9
N.A.
Protein Similarity:
100
64.1
99.7
93.7
N.A.
97.4
68.3
N.A.
89.2
N.A.
N.A.
N.A.
N.A.
49
N.A.
42.7
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
33.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
23
0
0
0
0
0
12
0
0
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
45
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
0
0
0
0
0
0
0
12
12
% D
% Glu:
0
0
0
56
0
0
56
12
0
12
0
0
0
0
12
% E
% Phe:
23
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
12
0
0
0
0
0
0
12
12
45
12
0
0
% H
% Ile:
12
12
23
0
12
0
0
0
0
0
12
12
0
34
0
% I
% Lys:
0
0
12
12
0
12
12
0
12
23
0
34
12
0
56
% K
% Leu:
0
56
45
0
45
0
0
0
12
0
12
0
0
45
0
% L
% Met:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
12
% M
% Asn:
0
0
0
0
12
12
0
23
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
45
12
0
0
0
0
% Q
% Arg:
0
0
0
12
0
0
0
0
12
0
0
0
0
0
0
% R
% Ser:
56
12
0
12
0
12
0
0
0
12
0
0
45
0
12
% S
% Thr:
12
0
0
0
12
0
0
0
0
0
0
12
12
0
0
% T
% Val:
0
0
12
0
0
45
12
12
23
0
12
0
12
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
23
0
23
45
45
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _